Isolation of human monoclonal antibodies from 4CMenB vaccinees reveals PorB and LOS as the main OMV components inducing cross-strain protection
We identified PorB and LOS as antigens on the OMV that may be implicated in the real-world observations of moderate protection against gonorrhea infection after OMV-based vaccinations.
Authors
- Elisabetta Frigimelica (ORCID: https://orcid.org/0000-0002-8173-3788)
- Sara Tomei (ORCID: https://orcid.org/0000-0002-5136-6876)
- Chiara Sammicheli
- Adriana Efron (ORCID: https://orcid.org/0000-0003-2513-9597)
- Oretta Finco (ORCID: https://orcid.org/0000-0002-8652-6534)
- Laura Santini (ORCID: https://orcid.org/0000-0002-9638-7275)
- Viola Viviani (ORCID: https://orcid.org/0000-0003-1517-9261)
- Giacomo Vezzani (ORCID: https://orcid.org/0000-0003-1142-598X)
- Elisa Faenzi
- Martina Audagnotto (ORCID: https://orcid.org/0000-0003-0555-4080)
- Nicola Pacchiani
- Alessia Biolchi
- Paolo Cinelli (ORCID: https://orcid.org/0000-0001-9099-9900)
- Isabel Delany
- Chiara Limongi (ORCID: https://orcid.org/0009-0008-5236-1736)
- Giulia Torricelli (ORCID: https://orcid.org/0000-0003-0695-8618)
- Alessandro Rossi (ORCID: https://orcid.org/0000-0001-8723-7622)
- Fabiola Giusti (ORCID: https://orcid.org/0000-0002-0466-6059)
- Simona Tavarini
Institutions
- Toscana Life Sciences (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1565862
- Citations
- 6
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 7.10