Case Report: Multidisciplinary discussion and management of a case involving a non-seminomatous germ cell tumor complicated by the presence of cancerous thrombus in the inferior vena cava

Testicular cancer predominantly manifests in younger males. It demonstrates a favorable response to cisplatin-based chemotherapy and exhibits a promising overall survival. Nevertheless, the emergence of certain rare complications, such as the development of an embolus in the vena cava due to cancer, suggests that the tumor exhibits a high degree of aggressiveness and is associated with a poorer prognosis. We present a case of stage IIIC mixed malignant germinoma with metastases to both lungs, left kidney, right paravascular iliac lymph nodes, periaortic lymph nodes, and an inferior vena cava tumor thrombus. Following Multi-disciplinary Team (MDT) discussion, treatment modalities including surgery and adjuvant chemotherapy were devised, resulting in optimal therapeutic outcomes without complications or significant adverse reactions.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-04-16
DOI
https://doi.org/10.3389/fonc.2025.1532983
Citations
1
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
2.01
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article

Case Report: Multidisciplinary discussion and management of a case involving a non-seminomatous germ cell tumor complicated by the presence of cancerous thrombus in the inferior vena cava

Shanhong Wan, Hong Zeng, Jindong Dai, Pengfei Shen et al.
1 citations
Frontiers in Oncology
Testicular diseases and treatments
2.01
article

Case Report: Multidisciplinary discussion and management of a case involving a non-seminomatous germ cell tumor complicated by the presence of cancerous thrombus in the inferior vena cava

Shanhong Wan, Hong Zeng, Jindong Dai, Pengfei Shen, Qiyu Zhu, Qian Wang, Ming Zhang
article en
1 citations

Abstract

Testicular cancer predominantly manifests in younger males. It demonstrates a favorable response to cisplatin-based chemotherapy and exhibits a promising overall survival. Nevertheless, the emergence of certain rare complications, such as the development of an embolus in the vena cava due to cancer, suggests that the tumor exhibits a high degree of aggressiveness and is associated with a poorer prognosis. We present a case of stage IIIC mixed malignant germinoma with metastases to both lungs, left kidney, right paravascular iliac lymph nodes, periaortic lymph nodes, and an inferior vena cava tumor thrombus. Following Multi-disciplinary Team (MDT) discussion, treatment modalities including surgery and adjuvant chemotherapy were devised, resulting in optimal therapeutic outcomes without complications or significant adverse reactions.

Frontiers in OncologyVol. 15
Sichuan University (CN), West China Hospital of Sichuan University (CN)
No poverty
Openalex Percentile: Top 17%
Testicular diseases and treatments
2.01
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