Case Report: Challenges of insulin and sulfonylurea dosing in an extremely premature infant for the management of KCNJ11-associated neonatal diabetes mellitus
This case report describes the unique and complicated clinical course of a premature neonate with an initially undifferentiated class of NDM requiring a microdose-based approach, i.e., a fraction of a regular dose, to both insulin and SU-based management. This report offers a concise recount of the applied diagnostic and therapeutic procedures while suggesting a decision tree for future NDM management in neonates.
Authors
- Ishan R Perera
- Hirenkumar Patel (ORCID: https://orcid.org/0000-0001-9395-9840)
- Melissa D. Garganta
- Brooke Jensen
Institutions
- Carilion Roanoke Memorial Hospital (US)
- Edward Via College of Osteopathic Medicine (US)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-04-16
- DOI
- https://doi.org/10.3389/fped.2025.1456818
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00