Analysis of the senescence secretome during zebrafish retina regeneration
Our data suggest that differential expression of SASP factors promotes initiation and progression of retina regeneration after both acute and chronic retinal damage. The existence of a common, overlapping set of 31 factors provides a group of novel therapeutic targets for retina regeneration studies.
Authors
- Kyle T Vallone (ORCID: https://orcid.org/0000-0002-8322-9075)
- James G. Patton (ORCID: https://orcid.org/0000-0001-5749-0870)
- Gregory Konar (ORCID: https://orcid.org/0000-0002-8808-8304)
- Tu Dac Nguyen
Institutions
- Vanderbilt University (US)
Publication Details
- Journal
- Frontiers in Aging
- Published
- 2025-04-16
- DOI
- https://doi.org/10.3389/fragi.2025.1569422
- Citations
- 2
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- Vanderbilt University
- National Institutes of Health