Gui-zhi-fu-ling-wan alleviates bleomycin-induced pulmonary fibrosis through inhibiting epithelial-mesenchymal transition and ferroptosis
GFW supplementation attenuated BLM-evoked lung injury and pulmonary fibrosis partially through repressing EMT and mtROS-mediated ferroptosis in pulmonary epithelial cells.
Authors
- Zhao-Wen Chen
- Lifang Cao (ORCID: https://orcid.org/0000-0002-1260-7366)
- Lin Fu (ORCID: https://orcid.org/0000-0003-1069-3560)
- Ya‐Lin Jiang
- Yan Wang (ORCID: https://orcid.org/0000-0002-9232-2212)
- Qian Zhang (ORCID: https://orcid.org/0000-0001-9924-6024)
- Rui Wang (ORCID: https://orcid.org/0000-0001-7015-0272)
- Yongxia Guo (ORCID: https://orcid.org/0000-0002-4737-6406)
- Mengmeng Ma (ORCID: https://orcid.org/0000-0003-1520-1289)
- Fenglian He
- Kui Liu (ORCID: https://orcid.org/0000-0002-7493-2244)
- Mei-Ling Xie
Institutions
- Anhui Medical University (CN)
- Bozhou People's Hospital (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.3389/fphar.2025.1552251
- Citations
- 1
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China