SUMOylation substrate encoding genes as prognostic biomarkers in pancreatic ductal adenocarcinoma with functional assessment of SAF-B2
This study underscores the role of SUMOylation in PDAC and introduces the Sscore as a prognostic tool. <i>SAFB2</i> is identified as a potential tumor suppressor, offering new therapeutic targets for PDAC.
Authors
- Chuanxin Yang (ORCID: https://orcid.org/0000-0003-3829-2961)
- Yangming Liu (ORCID: https://orcid.org/0009-0002-0742-9216)
- Jian Wang (ORCID: https://orcid.org/0000-0002-1902-1528)
- Xiangjun Wang (ORCID: https://orcid.org/0000-0001-6519-7893)
Institutions
- Shanghai Sixth People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.3389/fphar.2025.1532658
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China