Pre-transplant IE1-specific T-cell response and CD8+ T-cell count as predictive markers of treated HCMV reactivation in kidney transplant recipients

Lymphocyte counts and HCMV-specific T-cell response can be measured at pre-transplant in KTRs in order to efficiently predict the risk of treated HCMV reactivation during the first year after transplant. Potential cut-off and diagnostics algorithm should be better investigated in a large patients setting.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-04-16
DOI
https://doi.org/10.3389/fimmu.2025.1538795
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
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article

Pre-transplant IE1-specific T-cell response and CD8+ T-cell count as predictive markers of treated HCMV reactivation in kidney transplant recipients

Teresa Rampino, Marilena Gregorini, Fausto Baldanti, Daniele Lilleri et al.
Frontiers in Immunology
Cytomegalovirus and herpesvirus research
article

Pre-transplant IE1-specific T-cell response and CD8+ T-cell count as predictive markers of treated HCMV reactivation in kidney transplant recipients

Teresa Rampino, Marilena Gregorini, Fausto Baldanti, Daniele Lilleri, Maria Antonietta Grignano, Federica Zavaglio, Irene Cassanti
article en

Abstract

Lymphocyte counts and HCMV-specific T-cell response can be measured at pre-transplant in KTRs in order to efficiently predict the risk of treated HCMV reactivation during the first year after transplant. Potential cut-off and diagnostics algorithm should be better investigated in a large patients setting.

Frontiers in ImmunologyVol. 16
University of Pavia (IT), Policlinico San Matteo Fondazione (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Openalex Percentile: Top 89%
Cytomegalovirus and herpesvirus research
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Pre-transplant IE1-specific T-cell response and CD8+ T-cell count as predictive markers of treated HCMV reactivation in kidney transplant recipients — Teresa Rampino, Marilena Gregorini, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS