Dracaena trifasciata (Prain) Mabb leaf extract protects MIN6 pancreas-derived beta cells against the diabetic toxin streptozotocin: role of the NF-κB pathway
These data suggest that a leaf extract of <i>ST</i> has anti-diabetogenic efficacy, which may depend on the integrity of the NF-κB pathway. This protective effect appears to be impeded in a pro-inflammatory environment.
Authors
- Herson Antonio González-Ponce (ORCID: https://orcid.org/0000-0002-5202-4624)
- Nur Qomariyah (ORCID: https://orcid.org/0000-0003-0003-1870)
- Han Moshage (ORCID: https://orcid.org/0000-0002-4764-0246)
- André P. van Beek (ORCID: https://orcid.org/0000-0002-0335-8177)
- Gertjan van Dijk (ORCID: https://orcid.org/0000-0002-6565-4019)
- Christiaan Warner Hoornenborg
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Universitas Negeri Surabaya (ID)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.3389/fphar.2025.1485952
- Citations
- 1
- Primary Topic
- Natural Antidiabetic Agents Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Stichting De Cock-Hadders
- Rijksuniversiteit Groningen
- Universitair Medisch Centrum Groningen
- Direktorat Jenderal Pendidikan Tinggi