The impact of BST1 rs4698412 variant on Parkinson’s disease progression in a longitudinal study
PD patients carrying the <i>BST1</i> rs4698412 A-allelic variant showed more pronounced motor function deterioration than GG carriers, suggesting that <i>BST1</i> rs4698412 may serve as a genetic risk factor for disease progression in PD.
Authors
- Hao‐Ling Xu
- Guoen Cai (ORCID: https://orcid.org/0000-0002-0264-2125)
- Qin-yong Ye (ORCID: https://orcid.org/0009-0000-5663-0376)
- Yuancheng Weng (ORCID: https://orcid.org/0009-0009-5976-9491)
- Xiaoling Lin (ORCID: https://orcid.org/0000-0001-9084-7026)
- Lina Chen (ORCID: https://orcid.org/0000-0002-2423-2418)
- Xiaochun Chen (ORCID: https://orcid.org/0000-0001-5146-9288)
- Yunjing Li (ORCID: https://orcid.org/0000-0001-5747-6155)
- Jing Jian
- Yu Yang
- Ying-Qing Wang
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-04-16
- DOI
- https://doi.org/10.3389/fnagi.2025.1570347
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China