The Pathogenic Potential of <i>Slackia exigua</i> : A Case Study of Bacteremia in a Patient With Oral Infection

<i>Slackia exigua</i> is an anaerobic, Gram-positive, nonspore-forming bacterium that is typically part of the normal oral microbiota. It is generally considered biochemically inert and is often dismissed as a nonpathogenic contaminant in clinical cultures, particularly in respiratory samples. However, in this case study, we report a rare instance of <i>S</i>. <i>exigua</i> bacteremia in a patient with multiple medical comorbidities who was hospitalized after reporting to Emergency Department due to fatigue and right ear pain. The patient subsequently developed signs of persistent symptoms of septicemia, prompting an extensive investigation. Blood cultures identified <i>S</i>. <i>exigua</i> as the causative agent. This case underscores the importance of thorough culture workup and clinical correlation, especially in immunocompromised patients and patients with multiple medical comorbidities. Comprehensive dental care and the administration of targeted antibiotic therapy resulted in the patient's full recovery. This report highlights the potential pathogenic role of <i>S</i>. <i>exigua</i> in certain clinical scenarios and emphasizes the need for awareness of its possible implications in systemic infections.

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Publication Details

Journal
Case Reports in Infectious Diseases
Published
2025-01-01
DOI
https://doi.org/10.1155/crdi/2079663
Primary Topic
Streptococcal Infections and Treatments
Type
article
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article

The Pathogenic Potential of Slackia exigua : A Case Study of Bacteremia in a Patient With Oral Infection

Lisa Cornelius, Dhammika H. Navarathna, Gang Zhou
Case Reports in Infectious Diseases
Streptococcal Infections and Treatments
article

The Pathogenic Potential of Slackia exigua : A Case Study of Bacteremia in a Patient With Oral Infection

Lisa Cornelius, Dhammika H. Navarathna, Gang Zhou
article en

Abstract

<i>Slackia exigua</i> is an anaerobic, Gram-positive, nonspore-forming bacterium that is typically part of the normal oral microbiota. It is generally considered biochemically inert and is often dismissed as a nonpathogenic contaminant in clinical cultures, particularly in respiratory samples. However, in this case study, we report a rare instance of <i>S</i>. <i>exigua</i> bacteremia in a patient with multiple medical comorbidities who was hospitalized after reporting to Emergency Department due to fatigue and right ear pain. The patient subsequently developed signs of persistent symptoms of septicemia, prompting an extensive investigation. Blood cultures identified <i>S</i>. <i>exigua</i> as the causative agent. This case underscores the importance of thorough culture workup and clinical correlation, especially in immunocompromised patients and patients with multiple medical comorbidities. Comprehensive dental care and the administration of targeted antibiotic therapy resulted in the patient's full recovery. This report highlights the potential pathogenic role of <i>S</i>. <i>exigua</i> in certain clinical scenarios and emphasizes the need for awareness of its possible implications in systemic infections.

Case Reports in Infectious DiseasesVol. 2025(1)
Baylor Scott & White Medical Center - Temple (US), Central Texas Veterans Health Care System (US)
Good health and well-being
Openalex Percentile: Top 89%
Streptococcal Infections and Treatments
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The Pathogenic Potential of <i>Slackia exigua</i> : A Case Study of Bacteremia in a Patient With Oral Infection — Lisa Cornelius, Dhammika H. Navarathna, et al. · Case Reports in Infectious Diseases (2025) | TGRS Research Map | TGRS