Exploring the Mechanism of Qinzhuliangxue Mixture for Treating Skin Lesions in Atopic Dermatitis: Insights from Network Pharmacology and Experimental Validation
QZLX demonstrated a significant ability to mitigate AD-like skin lesions and effectively reduced serum levels of IgE, TSLP, and IL-4 in AD mice. The underlying mechanism of action may involve modulation via the JAK2/STAT3 pathway.
Authors
- Woon‐Puay Koh (ORCID: https://orcid.org/0000-0002-5674-6341)
- Yan‐Wei Xiang (ORCID: https://orcid.org/0000-0002-6250-5042)
- Yuting Li (ORCID: https://orcid.org/0009-0008-5686-2140)
- Zewen Chu (ORCID: https://orcid.org/0000-0002-8110-5298)
- Qiang He (ORCID: https://orcid.org/0000-0001-6481-0924)
- Xiang Li (ORCID: https://orcid.org/0000-0002-0016-6233)
- Hao Yin (ORCID: https://orcid.org/0009-0001-3282-9230)
- Yunxiao Qiao
- Lu Sun
- Haitang Zhang (ORCID: https://orcid.org/0009-0009-8824-5638)
- Jie Wang (ORCID: https://orcid.org/0000-0002-6126-5120)
- Aruncharoenphonchai Pottakorn
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Second People's Hospital (CN)
- Yueyang Hospital (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/jir.s509607
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fudan University