Causal relationship between Parkinson’s disease and gastric cancer: a Mendelian randomization study
Patients with Parkinson's disease may have a lower risk of developing gastric cancer, with P2X6 serving as a significant mediating variable. These novel insights can aid the development of potential therapeutic targets for patients with Parkinson's disease or gastric cancer.
Authors
- Lanjun Li (ORCID: https://orcid.org/0000-0001-7660-3500)
- Jiafeng Liu (ORCID: https://orcid.org/0000-0002-1030-5559)
- Ziyang Jiang
- Yunling Zhang (ORCID: https://orcid.org/0000-0001-8094-4164)
- Gang Yin (ORCID: https://orcid.org/0000-0001-9995-4629)
- Wenju Li (ORCID: https://orcid.org/0000-0002-6036-2690)
- Yuan Sun (ORCID: https://orcid.org/0009-0009-0518-9336)
- Jiayu Liu (ORCID: https://orcid.org/0000-0001-6976-4568)
Institutions
- Yangtze University (CN)
- People’s Hospital of Rizhao (CN)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1186/s12883-025-04184-7
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00