Xuebijing Alleviates Microglial Activation after Traumatic Brain Injuryvia Regulation of NF-κB Pathway: Network Pharmacology andExperimental Validation
These findings indicate that XBJ and HSYA may treat TBI by repressing microglial activation through the NF-κB pathway. Our study provides valuable evidence supporting XBJ as an effective therapy for TBI.
Authors
- Hongran Fu (ORCID: https://orcid.org/0009-0001-1226-4607)
- Dongkai Guo (ORCID: https://orcid.org/0000-0001-6736-5344)
- Xiaoyu Wang (ORCID: https://orcid.org/0009-0003-1706-7615)
- Jingwei Li (ORCID: https://orcid.org/0000-0002-2508-4859)
- Xuelin Mo
Institutions
- Nanjing Traditional Chinese Medicine Hospital (CN)
- Suzhou Municipal Hospital (CN)
- Changzhou No.2 People's Hospital (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-04-15
- DOI
- https://doi.org/10.2174/0113862073364997250324231219
- Citations
- 1
- Primary Topic
- Medicinal Plants and Bioactive Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.81