Association of Plasma Renin Activity with Risk of Late Hypertension in Pediatric Patients with Early Aortic Coarctation Repair: A Retrospective Study
Coarctation of the aorta is not just a simple mechanical obstruction of the aorta and should be seen and managed as a systemic disease. Abnormal preoperative renin concentrations were independently associated with the occurrence of HT at follow-up, suggesting that vascular dysfunction could play a role in hypertension development after successful CoA repair, negatively influencing the long-term prognostic of these patients.
Authors
- Tammam Youssef
- Ovidiu Ştiru (ORCID: https://orcid.org/0000-0002-5482-6794)
- Cristina Filip (ORCID: https://orcid.org/0000-0002-3824-1489)
- Radu Vlădăreanu (ORCID: https://orcid.org/0000-0001-9512-2673)
- Vlad Anton Iliescu (ORCID: https://orcid.org/0000-0001-9069-2722)
- Ancuța-Alina Constantin (ORCID: https://orcid.org/0009-0005-6742-6334)
- Irina-Maria Margarint
- Olguta Untaru
- Alexandru Popescu (ORCID: https://orcid.org/0000-0002-1734-4921)
- Iulian Rotaru
Institutions
- Carol Davila University of Medicine and Pharmacy (RO)
- Spitalului Clinic de Urgență pentru Copii Maria Sklodowska Curie (RO)
Publication Details
- Journal
- Life
- Published
- 2025-04-16
- DOI
- https://doi.org/10.3390/life15040656
- Citations
- 2
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71