The ability of anexelekto (AXL) expression and TERT promoter mutation to predict radioiodine-refractory differentiated thyroid carcinoma
Our predictive model highlights the association of elevated AXL expression, TERT promoter mutation, and an aggressive tumour subtype with the risk of RAI refractoriness. This information has the potential to aid in making informed treatment decisions. Furthermore, AXL is a potential therapeutic target for RAI-refractory disease.
Authors
- Bethy Suryawathy Hernowo (ORCID: https://orcid.org/0000-0003-2426-2534)
- Yohana Azhar (ORCID: https://orcid.org/0000-0003-2148-0202)
- Erwin Affandi Soeriadi (ORCID: https://orcid.org/0000-0003-2218-1861)
- Hasrayati Agustina (ORCID: https://orcid.org/0000-0001-8817-6753)
- Tutik Nur Ayni
Institutions
- Dr. Hasan Sadikin General Hospital (ID)
- Padjadjaran University (ID)
Publication Details
- Journal
- Diagnostic Pathology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1186/s13000-025-01643-0
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitas Padjadjaran