Cholinergic Degeneration and Cognitive Function in Early <scp><i>GBA1</i></scp>‐Related Parkinson's Disease
These results suggest an important role of early cholinergic denervation in GBA-PD patients, which is related to more severe cognitive dysfunction. ANN NEUROL 2025;98:398-409.
Authors
- Jeffrey M. Boertien (ORCID: https://orcid.org/0000-0002-9664-1771)
- Teus van Laar (ORCID: https://orcid.org/0000-0001-5088-480X)
- Giulia Carli (ORCID: https://orcid.org/0000-0001-7216-2031)
- Emile d’Angremont (ORCID: https://orcid.org/0000-0002-5468-8811)
- Anne C. Slomp (ORCID: https://orcid.org/0000-0002-1685-3986)
- Sygrid van der Zee (ORCID: https://orcid.org/0000-0002-4244-369X)
- Sofie Slingerland (ORCID: https://orcid.org/0000-0001-7443-4918)
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- University of Michigan (US)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1002/ana.27248
- Citations
- 2
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Michael J. Fox Foundation for Parkinson's Research