Predictive Factors for Super Responder Status and Long-Term Effectiveness of Guselkumab in Psoriasis: A Multicenter Retrospective Study
Our study highlights the importance of identifying patients most likely to achieve PASI 100 early in treatment. Factors such as obesity, prior biologic experience, and baseline PASI contribute to predicting complete skin clearance, which can guide clinical decision-making and enable personalized treatment strategies.
Authors
- Luca Bianchi (ORCID: https://orcid.org/0000-0001-8697-6896)
- Lorenzo Marcelli (ORCID: https://orcid.org/0009-0003-7635-5131)
- Francesco Loconsole (ORCID: https://orcid.org/0000-0003-2852-9451)
- Edoardo Mortato (ORCID: https://orcid.org/0009-0008-3763-6922)
- Maria Esposito (ORCID: https://orcid.org/0000-0002-4773-6993)
- Matteo Megna (ORCID: https://orcid.org/0000-0003-1803-2046)
- Claudio Bonifati (ORCID: https://orcid.org/0000-0001-7752-4337)
- Tommaso Bianchelli (ORCID: https://orcid.org/0000-0003-1323-0158)
- Anna Campanati (ORCID: https://orcid.org/0000-0002-3740-0839)
- Dario Buononato (ORCID: https://orcid.org/0000-0002-6223-5150)
- Nicoletta Bernardini (ORCID: https://orcid.org/0000-0002-6295-3574)
- Annunziata Raimondo (ORCID: https://orcid.org/0000-0002-0849-715X)
- Marina Talamonti (ORCID: https://orcid.org/0000-0002-3070-4071)
- Marco Galluzzo (ORCID: https://orcid.org/0000-0002-3424-5175)
- Nevena Skroza (ORCID: https://orcid.org/0000-0003-4478-5404)
- Luca Potestio (ORCID: https://orcid.org/0000-0001-5940-0592)
- Maria Concetta Fargnoli (ORCID: https://orcid.org/0000-0002-7249-2556)
- Nello Tommasino (ORCID: https://orcid.org/0009-0002-7997-1784)
- Viviana Lora (ORCID: https://orcid.org/0000-0002-7551-9750)
- Giacomo Caldarola (ORCID: https://orcid.org/0000-0002-8837-9232)
- Clara De Simone (ORCID: https://orcid.org/0000-0002-0898-0045)
- F. Primavera (ORCID: https://orcid.org/0000-0001-6253-8656)
- Eleonora De Luca (ORCID: https://orcid.org/0000-0003-3893-2869)
- Serena Lembo
- Anna Balato
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Rome Tor Vergata (IT)
- Marche Polytechnic University (IT)
- University of Salerno (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- University of L'Aquila (IT)
- Agostino Gemelli University Polyclinic (IT)
- Policlinico Tor Vergata (IT)
- San Gallicano Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto Nazionale di Riposo e Cura per Anziani (IT)
- University of Bari Aldo Moro (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Dermatology and Therapy
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1007/s13555-025-01394-2
- Citations
- 13
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 10.37