Performance of 2 Finger-Stick Blood Tests to Triage Adults With Symptoms of Pulmonary Tuberculosis: A Prospective Multisite Diagnostic Accuracy Study

Our results show that both Xpert-HR and the MBT are promising non-sputum-based point-of-care tests. The MBT met the World Health Organization target product profile for a triage test, which suggests it should be further developed.

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Publication Details

Journal
Clinical Infectious Diseases
Published
2025-03-07
DOI
https://doi.org/10.1093/cid/ciaf105
Citations
2
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
2.79

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article

Performance of 2 Finger-Stick Blood Tests to Triage Adults With Symptoms of Pulmonary Tuberculosis: A Prospective Multisite Diagnostic Accuracy Study

Joseph Akol, Anouk van Hooij, Stephanus T. Malherbe, Annemieke Geluk et al.
2 citations
Clinical Infectious Diseases
Tuberculosis Research and Epidemiology
2.79
article

Performance of 2 Finger-Stick Blood Tests to Triage Adults With Symptoms of Pulmonary Tuberculosis: A Prospective Multisite Diagnostic Accuracy Study

Joseph Akol, Anouk van Hooij, Stephanus T. Malherbe, Annemieke Geluk, Mark Hatherill, Kairaba Kanyi, Ngoc Le Hong, Bronwyn Smith, Paul L. A. M. Corstjens, Henry Ojiambo, Van Hoang Nguyen, J. Buech, Mary Nsereko, Joseph Mendy, Dang Thi Thanh Thao, Bernadine Fransman, Balie Carstens, Van Le, Tracy Richardson, Ha Vu Thi Ngoc, Susanne Tönsing, Gerhard Walzl, Humphrey Mulenga, Elizma Smit, Binta Sarr, Ousainou Cham, Salieu Barry, Amie Secka, Louise Pierneef, Novel N. Chegou, Nguyễn Thụy Thương Thương, Kate Hadley, Justin Shenje, Isaac L. Johnson, Karen M. Dobos, Awa Gindeh, Hau Nguyen Thi, Harriet Mayanja‐Kizza, Stanley Kimbung, Elma van Rooyen, Olumuyiwa Owolabi, Emmanuel Moreau, Thomas J. Scriba, Alhaji Jobe, Son Vo Thanh, Morten Rühwald, Gerard Tromp, Alicia Chetram, Momodou W. Jallow, Jayne S. Sutherland, Marika Finn, Helena Kuivaniemi, Rachel Oelofse, Simba Mabwe, Abdou K. Sillah, Andriëtte Hiemstra, Claudia Schacht, Le Hong Van, Abi-Janet Riley, Amadou Barry, Adam Penn‐Nicholson, Nicole Bilek, Michael Odie, Bintou Njai, Kim Stanley, Harriet Mayanja-Kizza, Monica Davies, Kim Stanley, Georgetta K. Daffeh, Momodou Rashid, Saidah Menya, Veronica Kizza, Yusuf Kironde, Deborah Banturaki, Immaculate Nahereza, Simon Okiror, Immaculate Kemigisha, Paul Mutumba, Lilian Murungi, Joan Nassuna, Gladys Mpalanyi
article en
2 citations

Abstract

Our results show that both Xpert-HR and the MBT are promising non-sputum-based point-of-care tests. The MBT met the World Health Organization target product profile for a triage test, which suggests it should be further developed.

Clinical Infectious DiseasesVol. 81(4)
South African Medical Research Council (ZA), FIND (CH), University of Cape Town (ZA), Stellenbosch University (ZA), Angkor Hospital for Children (KH), Leiden University Medical Center (NL), University of Oxford (GB), London School of Hygiene & Tropical Medicine (GB), South African Tuberculosis Vaccine Initiative (ZA), MRC Unit the Gambia (GM), Catalysis Foundation for Health (US), Oxford University Clinical Research Unit (VN), Makerere University (UG), Colorado State University (US)
Bill and Melinda Gates Foundation, London School of Hygiene and Tropical Medicine, University of Oxford, Universiteit Leiden, Universiteit Stellenbosch, National Institutes of Health, Medical Research Council, European and Developing Countries Clinical Trials Partnership
Good health and well-being
Openalex Percentile: Top 11%
Tuberculosis Research and Epidemiology
2.79
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