Triple-locked fluorescent probes sequentially activated by hNQO1, LAP and FA: application in bioimaging of cancer cells

Two fluorescent probes, subsequently activated by hNQO1, LAP and FA, were rationally designed for simultaneous detection of the above three analytes. Both probes could bioimage cancer cells overexpressing hNQO1, LAP and FA. Biotin-bearing probe NP3-Bio could discriminate between cancer cells and hypoxic normal cells.

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Publication Details

Journal
Chemical Communications
Published
2025-01-01
DOI
https://doi.org/10.1039/d5cc01546d
Citations
1
Primary Topic
Molecular Sensors and Ion Detection
Type
article
Field-Weighted Citation Impact
0.76
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article

Triple-locked fluorescent probes sequentially activated by hNQO1, LAP and FA: application in bioimaging of cancer cells

Junhong Qian, Langping Zhou, Han Chen, Weibing Zhang
1 citations
Chemical Communications
Molecular Sensors and Ion Detection
0.76
article

Triple-locked fluorescent probes sequentially activated by hNQO1, LAP and FA: application in bioimaging of cancer cells

Junhong Qian, Langping Zhou, Han Chen, Weibing Zhang
article en
1 citations

Abstract

Two fluorescent probes, subsequently activated by hNQO1, LAP and FA, were rationally designed for simultaneous detection of the above three analytes. Both probes could bioimage cancer cells overexpressing hNQO1, LAP and FA. Biotin-bearing probe NP3-Bio could discriminate between cancer cells and hypoxic normal cells.

Chemical CommunicationsVol. 61(41)
East China University of Science and Technology (CN)
Openalex Percentile: Top 32%
Molecular Sensors and Ion Detection
0.76
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