PD-1 Inhibitors for Periocular Squamous Cell Carcinoma With Perineural Spread to the Orbit and Skull Base

Treatment with PD-1 inhibitors can lead to meaningful responses in patients with periocular squamous cell carcinoma with perineural spread to the orbit and skull base and avoids the need for radiotherapy, which is toxic to the eye. Careful long-term follow-up is needed to assess long-term response durability.

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Publication Details

Journal
Ophthalmic Plastic and Reconstructive Surgery
Published
2025-04-16
DOI
https://doi.org/10.1097/iop.0000000000002944
Citations
7
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
9.48
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article

PD-1 Inhibitors for Periocular Squamous Cell Carcinoma With Perineural Spread to the Orbit and Skull Base

Renata Ferrarotto, Laura Gomez, Neal S. Akhave, Janet Fan et al.
7 citations
Ophthalmic Plastic and Reconstructive Surgery
Nonmelanoma Skin Cancer Studies
9.48
article

PD-1 Inhibitors for Periocular Squamous Cell Carcinoma With Perineural Spread to the Orbit and Skull Base

Renata Ferrarotto, Laura Gomez, Neal S. Akhave, Janet Fan, Tracy Lu, Sharia Hernandez, Luana Guimarães de Sousa, Bita Esmaeli, Oded Sagiv
article en
7 citations

Abstract

Treatment with PD-1 inhibitors can lead to meaningful responses in patients with periocular squamous cell carcinoma with perineural spread to the orbit and skull base and avoids the need for radiotherapy, which is toxic to the eye. Careful long-term follow-up is needed to assess long-term response durability.

Ophthalmic Plastic and Reconstructive SurgeryVol. 41(6)
The University of Texas MD Anderson Cancer Center (US)
Good health and well-being
Openalex Percentile: Top 2%
Nonmelanoma Skin Cancer Studies
9.48
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PD-1 Inhibitors for Periocular Squamous Cell Carcinoma With Perineural Spread to the Orbit and Skull Base — Renata Ferrarotto, Laura Gomez, et al. · Ophthalmic Plastic and Reconstructive Surgery (2025) | TGRS Research Map | TGRS