Operative vs Nonoperative Treatment of Acute Cholecystitis in Older Adults With Multimorbidity
The findings of this comparative effectiveness research study suggest that risk-adjusted operative treatment of acute cholecystitis in older patients with multimorbidity was associated with lower rates of 30- and 90-day readmissions and ED revisits compared with nonoperative treatment and a lower cost by 90 days. These findings further suggest that when uncertainty exists regarding the most appropriate treatment approach for this challenging population, strong consideration should be given to operative treatment.
Authors
- Luke Keele (ORCID: https://orcid.org/0000-0002-3859-2713)
- Emna Bakillah (ORCID: https://orcid.org/0000-0002-1847-4955)
- Drew Goldberg (ORCID: https://orcid.org/0000-0003-3768-3485)
- Rachael C. Acker (ORCID: https://orcid.org/0000-0002-1825-3183)
- Rachel Rapaport Kelz (ORCID: https://orcid.org/0000-0001-6635-5961)
- Elinore J. Kaufman (ORCID: https://orcid.org/0000-0001-7550-0024)
- Jasmine Hwang (ORCID: https://orcid.org/0000-0002-8546-2276)
- James Sharpe (ORCID: https://orcid.org/0000-0002-4357-718X)
- Sara P. Ginzberg (ORCID: https://orcid.org/0000-0003-1657-0617)
Institutions
- University of Pennsylvania Health System (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- JAMA Surgery
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1001/jamasurg.2025.0729
- Citations
- 7
- Primary Topic
- Gallbladder and Bile Duct Disorders
- Type
- article
- Field-Weighted Citation Impact
- 10.63