Estimated glucose disposal rate outperforms other insulin resistance surrogates in predicting incident cardiovascular diseases in cardiovascular-kidney-metabolic syndrome stages 0–3 and the development of a machine learning prediction model: a nation

The eGDR index outperforms six other IR indices in predicting CVD, heart disease, and stroke in individuals with CKM syndrome stages 0-3. Its incorporation into predictive models enhances risk stratification and may aid in the early identification of high-risk individuals in this population. Further studies are needed to validate these findings in external cohorts.

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Publication Details

Journal
Cardiovascular Diabetology
Published
2025-04-16
DOI
https://doi.org/10.1186/s12933-025-02729-1
Citations
32
Primary Topic
Blood Pressure and Hypertension Studies
Type
article
Field-Weighted Citation Impact
44.42
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article

Estimated glucose disposal rate outperforms other insulin resistance surrogates in predicting incident cardiovascular diseases in cardiovascular-kidney-metabolic syndrome stages 0–3 and the development of a machine learning prediction model: a nation

Enfa Zhao, Dong Chen, Bingtian Dong, Xiaocen Yang et al.
32 citations
Cardiovascular Diabetology
Blood Pressure and Hypertension Studies
44.42
article

Estimated glucose disposal rate outperforms other insulin resistance surrogates in predicting incident cardiovascular diseases in cardiovascular-kidney-metabolic syndrome stages 0–3 and the development of a machine learning prediction model: a nation

Enfa Zhao, Dong Chen, Bingtian Dong, Xiaocen Yang, Yuan Gao, Hua Zhang, Yuping Chen, Chaoxue Zhang
article en
32 citations

Abstract

The eGDR index outperforms six other IR indices in predicting CVD, heart disease, and stroke in individuals with CKM syndrome stages 0-3. Its incorporation into predictive models enhances risk stratification and may aid in the early identification of high-risk individuals in this population. Further studies are needed to validate these findings in external cohorts.

Cardiovascular DiabetologyVol. 24(1)
Dalian Medical University (CN), Anhui Medical University (CN), Westlake University (CN), Second Affiliated Hospital of Chongqing Medical University (CN), Zhongda Hospital Southeast University (CN), Zhongshan Hospital of Xiamen University (CN), First Affiliated Hospital of Anhui Medical University (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN), State Key Laboratory of Digital Medical Engineering (CN), Southeast University (CN), Chongqing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 0%
Blood Pressure and Hypertension Studies
44.42
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Estimated glucose disposal rate outperforms other insulin resistance surrogates in predicting incident cardiovascular diseases in cardiovascular-kidney-metabolic syndrome stages 0–3 and the development of a machine learning prediction model: a nation — Enfa Zhao, Dong Chen, et al. · Cardiovascular Diabetology (2025) | TGRS Research Map | TGRS