Chemical components and pharmacological action for Helianthus tuberosus and predictive analysis on its Q-markers

Helianthus tuberosus is a perennial herb that belongs to the Asteraceae family and Helianthus genus. It is cultivated in numerous northern and southern China regions, displaying numerous benefits such as its drought and frost resistance, ability to grow on most soils, and low fertilizer requirements. H. tuberosus contains various components, such as inulin, phenolic acids, terpenoids, flavonoids, steroids, phenylpropanoids, and other bioactive compounds with antioxidant, anti-inflammatory, antibacterial, anti-tumor, and immune-modulatory effects. In this paper, based on the new concept of quality marker (Q-marker) proposed by Academician Changxiao Liu, we analyzed the relationship between plant affinity, chemical composition specificity, traditional medicinal properties, and chemical composition measurability of H. tuberosus , and predicted its quality markers to provide a reference for the establishment of the quality evaluation system and comprehensive utilization of this herb.