Very Early Relapse (< 1 year) in de novo Metastatic Seminoma is Associated With Reduced Overall Survival
Relapse in seminoma occurred in 20% of all patients. In the initial metastatic stage, VER was associated with a higher metastatic burden at diagnosis compared to LR, leading to a reduced overall survival in VER. Consequently, treating physicians should be aware of these patients portending a worse prognosis, potentially discussing an early intensification of systemic treatment.
Authors
- Melanie von Brandenstein (ORCID: https://orcid.org/0000-0002-1499-7644)
- Axel Heidenreich (ORCID: https://orcid.org/0000-0002-2511-3664)
- Pia Paffenholz (ORCID: https://orcid.org/0000-0002-8209-7795)
- Felix Seelemeyer
- David Pfister
- Ruben Gößmann
Institutions
- Integrated Oncology (United States) (US)
- University Hospital Cologne (DE)
Publication Details
- Journal
- Clinical Genitourinary Cancer
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1016/j.clgc.2025.102347
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00