Striato-cortical connectivity patterns predict clinical profiles in Huntington’s disease
Distinct Huntington's disease clinical profiles can be characterized by predominantly motor-cognitive or behavioral disturbances, each related with unique functional and structural brain signatures. This substantiates that striato-cortical circuits exhibit functional interaction and potential reorganization.
Authors
- Matilde Calopa (ORCID: https://orcid.org/0000-0002-6943-3707)
- Ruth de Diego‐Balaguer (ORCID: https://orcid.org/0000-0002-2357-5195)
- Erdal Turan
- Nadia Rodríguez‐Dechicha
- Clara Garcia‐Gorro (ORCID: https://orcid.org/0000-0002-5271-4908)
- Audrey E. De Paepe (ORCID: https://orcid.org/0000-0002-1988-5916)
- Estela Càmara (ORCID: https://orcid.org/0000-0002-3879-0496)
- Irene Vaquer
- Alexis Pérez-Bellido (ORCID: https://orcid.org/0000-0002-5027-9455)
- Vasiliki Bikou
Institutions
- Universitat Autònoma de Barcelona (ES)
- Bellvitge University Hospital (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Duran i Reynals Hospital (ES)
- KU Leuven (BE)
Publication Details
- Journal
- NeuroImage Clinical
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.nicl.2025.103788
- Citations
- 1
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- Ministerio de Economía y Competitividad
- Instituto de Salud Carlos III
- European Regional Development Fund
- Agencia Estatal de Investigación