Biosynthesis of Oleanderaceae Represented by Vincristine and Clinical Applications

Vincristine, as a monoterpene indole alkaloid, has been widely used in various cancer treatments for its excellent antitumor efficacy.In this paper, we comprehensively review a comprehensive overview of the bisindole alkaloids from Oleaceae plants, exemplified by Vincristine, to explore their mechanisms of action, synthesis methods and clinical applications, as well as to look forward to their future development trends, aiming to provide references for Vincristine-related studies.