Stearyl amine coated liposome of rotigotine alleviates cognitive deficit in Parkinson’s disease induced mice model: modulation of oxidative stress, and motor coordination
The cationic liposome RTG-LP3 demonstrated effective delivery of liposomes with superior therapeutic effects in treating PD <i>via</i> nasal route. These findings highlight the potential of cationic liposomes as a viable method for improving brain penetration and neuroprotection in PD therapy.
Authors
- Gopika Gopan (ORCID: https://orcid.org/0000-0001-6046-0656)
- Jobin Jose (ORCID: https://orcid.org/0000-0002-2815-5384)
- Prajna Shastry (ORCID: https://orcid.org/0000-0001-7810-5230)
- Kartik Bhairu Khot
- Harsha Ashtekar (ORCID: https://orcid.org/0000-0002-5809-6389)
- Chaithra Raviraj (ORCID: https://orcid.org/0000-0003-3603-7967)
- D S Sandeep
Institutions
- Nitte University (IN)
Publication Details
- Journal
- Drug Development and Industrial Pharmacy
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1080/03639045.2025.2494127
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39