Experimental Investigation of Hematological Toxicity After Radiation Therapy Combined With Immune Checkpoint Inhibitors
These findings suggest that combining ICIs with RT does not exacerbate hematological toxicity. This information is valuable for interpreting adverse events in clinical trials involving radioimmunotherapy and for predicting potential hematological side effects in cancer patients receiving these treatments.
Authors
- Katja Steiger (ORCID: https://orcid.org/0000-0002-7269-5433)
- Stephanie E. Combs (ORCID: https://orcid.org/0000-0002-5233-1536)
- Thomas E. Schmid (ORCID: https://orcid.org/0000-0002-8894-8087)
- Sarah Diederich (ORCID: https://orcid.org/0000-0002-1546-492X)
- Sophie M. Nefzger (ORCID: https://orcid.org/0000-0002-9571-5783)
- Julius Fischer (ORCID: https://orcid.org/0000-0002-6951-3416)
- Ziyi Huang (ORCID: https://orcid.org/0000-0002-1678-3463)
- Vincent R. Timnik
- Guido Kroemer
- Maximilian Giller
- Nicole A Schmid (ORCID: https://orcid.org/0009-0002-7461-7321)
- Andreas Zoeschg
Institutions
- Inserm (FR)
- German Cancer Research Center (DE)
- Université Paris Cité (FR)
- Heidelberg University (DE)
- Université Paris-Saclay (FR)
- TUM Klinikum (DE)
- Helmholtz Zentrum München (DE)
- Sorbonne Université (FR)
- Centre de Recherche des Cordeliers (FR)
- Technical University of Munich (DE)
Publication Details
- Journal
- International Journal of Radiation Oncology*Biology*Physics
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1016/j.ijrobp.2025.04.008
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Else Kröner-Fresenius-Stiftung
- Deutsche Krebshilfe