A DIAGNOSTIC DILEMMA: RECURRENT HYPOKALEMIC WEAKNESS SECONDARY TO SJOGREN'S SYNDROME (A DRTA EFFECT)

Renal involvement occurs in approximately 5% of patients with Sjogren’s syndrome (SS). Renal lesions that predominate are tubulointerstitial nephritis and membranoproliferative glomerulonephritis. We report the case of a 50-year-old female who presented with weakness of lower limbs. A diagnosis of distal renal tubular acidosis type 1 (DTA1) secondary to SS was made, discovered in view of hypokalemic paralysis. The patient was treated symptomatically with injectable potassium chloride sodium bicarbonate. Corticosteroid and hydroxychloroquine were used to treat SS. The patient improved with correction of acidosis and hypokalemia.

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Journal
International Journal of Current Pharmaceutical Research
Published
2025-03-15
DOI
https://doi.org/10.22159/ijcpr.2025v17i2.6071
Primary Topic
Salivary Gland Disorders and Functions
Type
article
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article

A DIAGNOSTIC DILEMMA: RECURRENT HYPOKALEMIC WEAKNESS SECONDARY TO SJOGREN'S SYNDROME (A DRTA EFFECT)

Puneet R. Shah, Sanjaykumar Somsingbhai Rathwa, PRATIKSHA RATHWA, MAULIK KUMAR KARPATIYA
International Journal of Current Pharmaceutical Research
Salivary Gland Disorders and Functions
article

A DIAGNOSTIC DILEMMA: RECURRENT HYPOKALEMIC WEAKNESS SECONDARY TO SJOGREN'S SYNDROME (A DRTA EFFECT)

Puneet R. Shah, Sanjaykumar Somsingbhai Rathwa, PRATIKSHA RATHWA, MAULIK KUMAR KARPATIYA
article en

Abstract

Renal involvement occurs in approximately 5% of patients with Sjogren’s syndrome (SS). Renal lesions that predominate are tubulointerstitial nephritis and membranoproliferative glomerulonephritis. We report the case of a 50-year-old female who presented with weakness of lower limbs. A diagnosis of distal renal tubular acidosis type 1 (DTA1) secondary to SS was made, discovered in view of hypokalemic paralysis. The patient was treated symptomatically with injectable potassium chloride sodium bicarbonate. Corticosteroid and hydroxychloroquine were used to treat SS. The patient improved with correction of acidosis and hypokalemia.

International Journal of Current Pharmaceutical Research
Suamandeep Vidyapeeth University (IN), Bharati Vidyapeeth (Deemed to be University) (IN)
Openalex Percentile: Top 90%
Salivary Gland Disorders and Functions
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