Evaluation of Onco E6 point of care rapid diagnostic test for human papilloma virus in Bahir Dar, Amhara Regional State, Ethiopia
The HPV 16/18 OncoE6™ Cervical test kit test had sub-optimum sensitivity and high specificity for detection of cervical precancer and cancer cases. The sensitivity of the kit could be increased by incorporating other more prevalent genotypes like genotype 52, 58, 31 and 35. The HPV16/18-E6 test could be used either as primary screening tool or in conjunction with other diagnostic methods.
Authors
- Endalkachew Nibret (ORCID: https://orcid.org/0000-0002-7063-2877)
- Gizachew Yismaw
- Belay Bezabih (ORCID: https://orcid.org/0000-0002-9287-9213)
- Bereket Amare
- Alemayehu Abate (ORCID: https://orcid.org/0000-0003-4159-6288)
- Abaineh Munshea (ORCID: https://orcid.org/0000-0002-1469-2189)
Institutions
- Amhara Regional Health Bureau (ET)
- Amhara Agricultural Research Institute (ET)
- Bahir Dar University (ET)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1371/journal.pone.0321076
- Citations
- 2
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 2.71