Genome-Wide Study of the UK Biobank Highlights the Importance of the Homeobox-C Gene Cluster in Hip Fracture Risk
Polymorphisms affecting homeobox-C cluster genes influence hip fracture risk in the general population. Future research should focus on validating these genetic associations and exploring optimal therapeutic interventions that could mitigate fracture risk in subpopulations carrying these polymorphisms.
Authors
- Michael Fertleman (ORCID: https://orcid.org/0000-0003-4023-1156)
- Ping Zhang (ORCID: https://orcid.org/0000-0001-7063-7769)
- Matteo Di Giovannantonio (ORCID: https://orcid.org/0000-0003-3678-652X)
- Louis Koizia (ORCID: https://orcid.org/0000-0003-4074-6926)
- Benjamin Harris (ORCID: https://orcid.org/0000-0002-8154-8953)
Institutions
- Centre for Human Genetics (GB)
- University of Oxford (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Geriatric Orthopaedic Surgery & Rehabilitation
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1177/21514593251336568
- Citations
- 3
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 5.16