Features of pregnancy management with familial hypercholesterolemia: a case report
Familial hypercholesterolemia is an autosomal dominant disorder of lipid metabolism, leading to an increase in plasma low-density lipoprotein cholesterol, followed by premature atherosclerosis. In women with familial hypercholesterolemia, pregnancy and lactation pose an additional risk due to the association of physiological changes, pre-existing dyslipidemia, and limited therapeutic options and experience. A clinical case of successful management of a pregnant woman with familial hypercholesterolemia against the background of multifocal atherosclerosis with an assessment of the dynamics of the lipid profile at different stages of pregnancy and after childbirth is presented.
Authors
- О. В. Цыганкова (ORCID: https://orcid.org/0000-0003-0207-7063)
- Н. М. Пасман (ORCID: https://orcid.org/0000-0002-6095-1954)
- Е. Н. Березикова (ORCID: https://orcid.org/0000-0002-9630-0213)
- С. Н. Шилов (ORCID: https://orcid.org/0000-0002-7777-6419)
- N. F. Yakovleva
Institutions
- Novosibirsk State Medical University (RU)
- Novosibirsk State University (RU)
Publication Details
- Journal
- Siberian Journal of Clinical and Experimental Medicine
- Published
- 2025-04-13
- DOI
- https://doi.org/10.29001/2073-8552-2025-40-1-159-165
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00