Features of pregnancy management with familial hypercholesterolemia: a case report

Familial hypercholesterolemia is an autosomal dominant disorder of lipid metabolism, leading to an increase in plasma low-density lipoprotein cholesterol, followed by premature atherosclerosis. In women with familial hypercholesterolemia, pregnancy and lactation pose an additional risk due to the association of physiological changes, pre-existing dyslipidemia, and limited therapeutic options and experience. A clinical case of successful management of a pregnant woman with familial hypercholesterolemia against the background of multifocal atherosclerosis with an assessment of the dynamics of the lipid profile at different stages of pregnancy and after childbirth is presented.

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Publication Details

Journal
Siberian Journal of Clinical and Experimental Medicine
Published
2025-04-13
DOI
https://doi.org/10.29001/2073-8552-2025-40-1-159-165
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Features of pregnancy management with familial hypercholesterolemia: a case report

О. В. Цыганкова, Н. М. Пасман, Е. Н. Березикова, С. Н. Шилов et al.
Siberian Journal of Clinical and Experimental Medicine
Lipoproteins and Cardiovascular Health
article

Features of pregnancy management with familial hypercholesterolemia: a case report

О. В. Цыганкова, Н. М. Пасман, Е. Н. Березикова, С. Н. Шилов, N. F. Yakovleva
article en

Abstract

Familial hypercholesterolemia is an autosomal dominant disorder of lipid metabolism, leading to an increase in plasma low-density lipoprotein cholesterol, followed by premature atherosclerosis. In women with familial hypercholesterolemia, pregnancy and lactation pose an additional risk due to the association of physiological changes, pre-existing dyslipidemia, and limited therapeutic options and experience. A clinical case of successful management of a pregnant woman with familial hypercholesterolemia against the background of multifocal atherosclerosis with an assessment of the dynamics of the lipid profile at different stages of pregnancy and after childbirth is presented.

Siberian Journal of Clinical and Experimental MedicineVol. 40(1)
Novosibirsk State Medical University (RU), Novosibirsk State University (RU)
Openalex Percentile: Top 87%
Lipoproteins and Cardiovascular Health
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Features of pregnancy management with familial hypercholesterolemia: a case report — О. В. Цыганкова, Н. М. Пасман, et al. · Siberian Journal of Clinical and Experimental Medicine (2025) | TGRS Research Map | TGRS