Optimised medical therapy alone versus optimised medical therapy plus revascularisation for asymptomatic or low-to-intermediate risk symptomatic carotid stenosis (ECST-2): 2-year interim results of a multicentre randomised trial
National Institute for Health and Care Research; Stroke Association; Swiss National Science Foundation; Dutch Organisation for Knowledge and Innovation in Health, Healthcare and Well-Being; Leeds Neurology Foundation.
Authors
- Francesca B. Pizzini (ORCID: https://orcid.org/0000-0002-6285-0989)
- Audinga‐Dea Hazewinkel (ORCID: https://orcid.org/0000-0002-6923-4388)
- Marina Maurer
- M. Eline Kooi (ORCID: https://orcid.org/0000-0001-7562-5724)
- Bart J. Emmer (ORCID: https://orcid.org/0000-0001-8462-4037)
- Toby Richards (ORCID: https://orcid.org/0000-0001-9872-4653)
- Paul J. Nederkoorn (ORCID: https://orcid.org/0000-0001-7386-4545)
- Gert J. de Borst (ORCID: https://orcid.org/0000-0002-1389-4141)
- Maaike Scheele
- Martin M. Brown (ORCID: https://orcid.org/0000-0002-3273-1356)
- John Gregson (ORCID: https://orcid.org/0000-0001-6084-166X)
- Gwynedd E. Pickett (ORCID: https://orcid.org/0000-0002-5896-1782)
- Philippe Lyrer (ORCID: https://orcid.org/0000-0002-1435-1114)
- Gemma Smith
- John Bamford (ORCID: https://orcid.org/0000-0002-7817-8832)
- Hans Rolf Jäger (ORCID: https://orcid.org/0000-0002-6403-4184)
- Twan J. van Velzen
- Simone J. A. Donners
- Laurine van der Steen
- Gareth Tervit
- Leo Hermann Bonati (ORCID: https://orcid.org/0000-0003-1163-8133)
- Bob Roozenbeek (ORCID: https://orcid.org/0000-0002-8320-8303)
- Suk Fun Cheng (ORCID: https://orcid.org/0000-0002-9061-1723)
- Robert Simister (ORCID: https://orcid.org/0000-0003-0578-6711)
- Gordon Gubitz
Institutions
- University of Verona (IT)
- Dalhousie University (CA)
- University College London Hospitals NHS Foundation Trust (GB)
- University of East London (GB)
- Utrecht University (NL)
- Leeds Teaching Hospitals NHS Trust (GB)
- County Durham and Darlington NHS Foundation Trust (GB)
- Maastricht University Medical Centre (NL)
- Queen Elizabeth II Health Sciences Centre (CA)
- Erasmus MC (NL)
- University Hospital of Basel (CH)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- London School of Hygiene & Tropical Medicine (GB)
- UK Dementia Research Institute (GB)
- South Tyneside and Sunderland NHS Foundation Trust (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- Amsterdam University Medical Centers (NL)
- Reha Rheinfelden (CH)
- University College London (GB)
Publication Details
- Journal
- The Lancet Neurology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1016/s1474-4422(25)00107-3
- Citations
- 49
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 74.40
Funders
- National Science Foundation
- National Institute for Health and Care Research
- Stroke Association
- University College London
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- ZonMw
- University College London Hospitals NHS Foundation Trust
- Research for Patient Benefit Programme