Synthesis of quinoline derivatives by palladium-catalyzed isocyanide insertion/undirected C(sp<sup>2</sup>)–H functionalization/[4 + 1] cyclization reactions involving aryl isocyanide

The study reports a novel strategy for a palladium-catalyzed aryl isocyanide insertion reaction by integrating the C(sp 2 )–H functionalization reaction with the [4 + 1] cyclization reaction, thereby opening up a brand-new route for the efficient synthesis of quinoline derivatives.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-01-01
DOI
https://doi.org/10.1039/d5qo00349k
Citations
3
Primary Topic
Catalytic C–H Functionalization Methods
Type
article
Field-Weighted Citation Impact
2.81
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article

Synthesis of quinoline derivatives by palladium-catalyzed isocyanide insertion/undirected C(sp2)–H functionalization/[4 + 1] cyclization reactions involving aryl isocyanide

K Li, Shanshan Liu, Ping He, Jiangnan Zheng et al.
3 citations
Organic Chemistry Frontiers
Catalytic C–H Functionalization Methods
2.81
article

Synthesis of quinoline derivatives by palladium-catalyzed isocyanide insertion/undirected C(sp2)–H functionalization/[4 + 1] cyclization reactions involving aryl isocyanide

K Li, Shanshan Liu, Ping He, Jiangnan Zheng, Long Wang, Zhi‐Lin Ren, Yong‐Jie Wu, Jun Wu, Shaojie Jiang
article en
3 citations

Abstract

The study reports a novel strategy for a palladium-catalyzed aryl isocyanide insertion reaction by integrating the C(sp 2 )–H functionalization reaction with the [4 + 1] cyclization reaction, thereby opening up a brand-new route for the efficient synthesis of quinoline derivatives.

Organic Chemistry FrontiersVol. 12(17)
China Three Gorges University (CN), Hubei University of Arts and Science (CN)
Openalex Percentile: Top 11%
Catalytic C–H Functionalization Methods
2.81
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