Phytochemical Profile and Antioxidant Potential of Berberis aristata Bark in Diabetes Mellitus Management

Diabetes mellitus is a long known metabolic disorder that is afflicting millions of people all over the world. High levels of blood sugar (also known as glucose) in the blood that can develop into other health problems if untreated, this is the main feature. In this case the body cannot make enough insulin to regulate blood sugar or does not use insulin properly. Diabetes have two types, i.e. diabetes 1st type and diabetes 2nd type. Chronic diseases both are called diabetes that affect how glucose is processed in the body causing blood sugar levels to be high. They however have different causes, symptoms, and treatment options.A plant of the Berberidaceae family, Berberis aristata is often called Indian Barberry or Tree Turmeric. The traditional use of Berberis aristata has been very long. One of its many active ingredients, berberine has shown antimicrobial, anti inflammatory as well as antioxidant and antidiabetic properties. The plant is used for treating numerous medical conditions, e.g. digestive problems, respiratory infections, skin conditions, diabetes. The Berberis aristata in ayurvedic medicine is used in diabetes and diabetes related complications. It is understood to improve insulin sensitivity and to promote glucose uptake by the cells to help with blood sugar levels. Berberis aristata is a long traditional medicine. Antimicrobial, antidiabetic, antioxidant and anti-inflammatory properties have been demonstrated for one of its many active ingredients, berberine, although it is not believed to be the most important one when it comes to diabetes. The plant is used for treatment of numerous medical conditions such as digestive, respiratory infection, skin, and diabetes. Keywords: Diabetes mellitus, Antioxidant, Berberine, Berberis aristata