Oxygen Extraction and Blood Transport in the Human Retina: A Mathematical Modelling and Analysis

This study aims to describe the intricate flow of blood within the retinal tissue. The main findings of this research are the introduction of a quantitative method to calculate total oxygen extraction using retinal measurements of total blood flow, providing a crucial link between blood flow dynamics and oxygen transport. To analyze the problem, the authors employ a perturbation procedure, a mathematical approach that simplifies complex systems by introducing small changes to the variables. This approach facilitates a deeper understanding of the interplay between flow mechanics and oxygen delivery in the retina. The study's findings hold potential for advancing knowledge in retinal physiology and could pave the way for improved diagnostic and therapeutic strategies for retinal vascular diseases.