Towards Precision Cardiovascular Medicine - A Novel Framework for Risk Prediction Using MultiOmics and Imaging Data

The framework integrated multi-omics data and imaging characteristics to boost predictive precision for cardiovascular risk. Existing studies chiefly relied on restricted clinical information using common logistic regression designs unable to capture cardiovascular diseases (CVD's) intricacy. Such dated techniques experienced diminished accuracy and lack personalized risk prediction. But these restrictions are surpassed by the suggested system since it uses deep learning algorithms such as Random Forest, Convolutional Neural Networks (CNN) and Recurrent Neural Networks (RNN) for structured data and visual information. To prepare the data, standardization and simplification of complexity firstly applied preprocessing techniques such as PCA and t-SNE first, before utilizing feature selection via RFE and LASSO. Results demonstrated substantially improved outcomes with 0.85 accuracy, 0.82 sensitivity and an AUC-ROC of 0.90, delivering a more trustworthy tool for early intervention and customized cardiovascular care. Complex sentences mixed with shorter, simpler constructions to vary structure and keep readers engaged throughout the lengthier description.

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Publication Details

Published
2025-03-04
DOI
https://doi.org/10.1109/autocom64127.2025.10956582
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
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article

Towards Precision Cardiovascular Medicine - A Novel Framework for Risk Prediction Using MultiOmics and Imaging Data

S. D. Lalitha, Sarv Priya, S. Navaneethan, G R Abijith et al.
Cardiac Imaging and Diagnostics
article

Towards Precision Cardiovascular Medicine - A Novel Framework for Risk Prediction Using MultiOmics and Imaging Data

S. D. Lalitha, Sarv Priya, S. Navaneethan, G R Abijith, Akhouri Pramod Krishna, V. Sujay
article en

Abstract

The framework integrated multi-omics data and imaging characteristics to boost predictive precision for cardiovascular risk. Existing studies chiefly relied on restricted clinical information using common logistic regression designs unable to capture cardiovascular diseases (CVD's) intricacy. Such dated techniques experienced diminished accuracy and lack personalized risk prediction. But these restrictions are surpassed by the suggested system since it uses deep learning algorithms such as Random Forest, Convolutional Neural Networks (CNN) and Recurrent Neural Networks (RNN) for structured data and visual information. To prepare the data, standardization and simplification of complexity firstly applied preprocessing techniques such as PCA and t-SNE first, before utilizing feature selection via RFE and LASSO. Results demonstrated substantially improved outcomes with 0.85 accuracy, 0.82 sensitivity and an AUC-ROC of 0.90, delivering a more trustworthy tool for early intervention and customized cardiovascular care. Complex sentences mixed with shorter, simpler constructions to vary structure and keep readers engaged throughout the lengthier description.

Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology (IN), Krishna University (IN), St. Joseph's Institute of Technology (IN), Saveetha University (IN)
Good health and well-being
Openalex Percentile: Top 88%
Cardiac Imaging and Diagnostics
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