The Association between Multiple Environmental Exposures and Symptoms of Generalized Anxiety Disorder in a Prospective, US-Based Cohort Study
In this population, higher levels of summer greenness and nSES may be protectively associated with GAD symptoms, whereas medium- and long-term <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mrow><mml:mi>NO</mml:mi></mml:mrow></mml:mrow><mml:mn>2</mml:mn></mml:msub></mml:mrow></mml:mrow></mml:math> exposure, long-term temperature, and walkability are adversely associated with GAD symptoms. Socioeconomically deprived areas may bear additional risks. The results of the quantile g-computation analysis suggest that environmental exposures may act antagonistically with one another in relation to GAD symptoms. https://doi.org/10.1289/EHP14458.
Authors
- Peter James (ORCID: https://orcid.org/0000-0002-2858-1973)
- Jeff D. Yanosky
- Francine Laden
- Brent A. Coull (ORCID: https://orcid.org/0000-0002-1808-4156)
- Grete E. Wilt (ORCID: https://orcid.org/0000-0002-7145-6975)
- Olivia I. Okereke (ORCID: https://orcid.org/0000-0002-9523-2693)
- Nicole V. DeVille (ORCID: https://orcid.org/0000-0002-2199-8805)
- Charlotte Roscoe (ORCID: https://orcid.org/0000-0002-9169-6458)
- Joel D. Kaufman (ORCID: https://orcid.org/0000-0003-4174-9037)
- Isabel Holland (ORCID: https://orcid.org/0000-0002-6416-7729)
- Unnati Mehta (ORCID: https://orcid.org/0000-0002-0727-4413)
- Hari S. Iyer (ORCID: https://orcid.org/0000-0002-7596-9049)
- Melissa R. Fiffer (ORCID: https://orcid.org/0000-0003-0188-5229)
- Jaime E. Hart
Institutions
- Rutgers, The State University of New Jersey (US)
- Brigham and Women's Hospital (US)
- Pennsylvania State University (US)
- Harvard University (US)
- University of Washington (US)
- Harvard University Press (US)
- Massachusetts General Hospital (US)
- Harvard Pilgrim Health Care (US)
- Dana-Farber Cancer Institute (US)
- Rutgers Cancer Institute (US)
Publication Details
- Journal
- Environmental Health Perspectives
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1289/ehp14458
- Citations
- 2
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 2.40
Funders
- National Institutes of Health