Prognostic role of interim PET-CT demonstrating partial metabolic response in diffuse large B-Cell lymphoma: a retrospective study
Our study revealed that within the cohort of DLBCL patients exhibiting PMR on interim PET scans, an interim RLL greater than 1.66 and bone marrow involvement emerged as independent risk factors for positive PET results at the end of treatment. Additionally, the IPI and interim RLL were identified as independent prognostic markers for both progression-free survival and overall survival. The integration of clinical characteristics with semi-quantitative PET/CT parameters has the potential to enhance the prognostic role of interim PET/CT exhibiting PMR in DLBCL cases.
Authors
- Jinjie Gao (ORCID: https://orcid.org/0000-0002-6043-4463)
- Huabin Hu (ORCID: https://orcid.org/0000-0003-1352-2206)
- Shuozi Liu
- Mei‐Xin Zhao (ORCID: https://orcid.org/0000-0001-9182-8214)
- Hongmei Jing (ORCID: https://orcid.org/0000-0002-1795-5650)
Institutions
- Peking University (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Annals of Hematology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1007/s00277-025-06368-0
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00