Impact of Pharmacogenetics on Pharmacokinetics of First-Line Antituberculosis Drugs in the HIRIF Trial
A tag SNP approach may offer simpler and cheaper prediction of INH PK. Further exploration of the impact of SLCO1B1 SNPs on RIF PK is required in this and other populations. Clinical Trials Registration. NCT01408914.
Authors
- Henry Pertinez
- Elsa Delgado-Sánchez (ORCID: https://orcid.org/0000-0002-5079-8511)
- Elizabeth A. Mackay
- Elna Osso
- Karen Tintaya
- Diana Vargas (ORCID: https://orcid.org/0000-0003-0668-5664)
- Carole D. Mitnick (ORCID: https://orcid.org/0000-0002-3455-658X)
- Leonid Lecca (ORCID: https://orcid.org/0000-0003-1363-3985)
- Charles A. Peloquin (ORCID: https://orcid.org/0000-0001-9002-7052)
- Judith Jiménez (ORCID: https://orcid.org/0000-0001-7633-8401)
- Gustavo E. Velásquez (ORCID: https://orcid.org/0000-0003-1438-0692)
- M B Brooks
- Julia Coit (ORCID: https://orcid.org/0000-0002-9837-8444)
- Róger Calderón (ORCID: https://orcid.org/0000-0001-8932-0489)
- Geraint Davies (ORCID: https://orcid.org/0000-0002-3819-490X)
- Georgina Platt
- David García (ORCID: https://orcid.org/0000-0002-7820-050X)
Institutions
- Boston University (US)
- Harvard University (US)
- University of Liverpool (GB)
- University of California, San Francisco (US)
- University of Florida (US)
- Hospital Nacional Cayetano Heredia (PE)
- EsSALUD (PE)
- Harvard Global Health Institute (US)
- Universidad Privada Sergio Bernales (PE)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1093/infdis/jiaf195
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.40