Transcriptomic profiles of Crandell-Rees feline kidney cells infected with Varicellovirus felidalpha-1 (FHV-1) field and vaccine strains

This study demonstrates the host and viral gene expressions during FHV-1 infection shows the distinct host responses to field and vaccine strains using an in vitro model. These findings provide a foundation for future transcriptomic investigations in other cell types, including ex-vivo explants systems, to enhance our understanding of host and viral factors contributing to disease outcomes.

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Publication Details

Journal
Virology Journal
Published
2025-04-16
DOI
https://doi.org/10.1186/s12985-025-02722-w
Primary Topic
Viral Infections and Vectors
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptomic profiles of Crandell-Rees feline kidney cells infected with Varicellovirus felidalpha-1 (FHV-1) field and vaccine strains

Emily Kwan, Alistair R. Legione, Joanne M. Devlin, Carol A. Hartley
Virology Journal
Viral Infections and Vectors
article

Transcriptomic profiles of Crandell-Rees feline kidney cells infected with Varicellovirus felidalpha-1 (FHV-1) field and vaccine strains

Emily Kwan, Alistair R. Legione, Joanne M. Devlin, Carol A. Hartley
article en

Abstract

This study demonstrates the host and viral gene expressions during FHV-1 infection shows the distinct host responses to field and vaccine strains using an in vitro model. These findings provide a foundation for future transcriptomic investigations in other cell types, including ex-vivo explants systems, to enhance our understanding of host and viral factors contributing to disease outcomes.

Virology JournalVol. 22(1)
The University of Melbourne (AU)
Zero hunger
Openalex Percentile: Top 89%
Viral Infections and Vectors
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