Transcriptomic profiles of Crandell-Rees feline kidney cells infected with Varicellovirus felidalpha-1 (FHV-1) field and vaccine strains
This study demonstrates the host and viral gene expressions during FHV-1 infection shows the distinct host responses to field and vaccine strains using an in vitro model. These findings provide a foundation for future transcriptomic investigations in other cell types, including ex-vivo explants systems, to enhance our understanding of host and viral factors contributing to disease outcomes.
Authors
- Emily Kwan (ORCID: https://orcid.org/0000-0002-6201-9415)
- Alistair R. Legione (ORCID: https://orcid.org/0000-0003-2407-4496)
- Joanne M. Devlin
- Carol A. Hartley (ORCID: https://orcid.org/0000-0001-6174-7341)
Institutions
- The University of Melbourne (AU)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1186/s12985-025-02722-w
- Primary Topic
- Viral Infections and Vectors
- Type
- article
- Field-Weighted Citation Impact
- 0.00