Mapping the role of macro and micronutrients in bone mineral density: a comprehensive Mendelian randomization study
Our findings suggest that appropriate levels of plasma vitamin B12 and adequate levels of serum selenium are crucial for delaying bone loss and promoting bone health, emphasizing the need for nutritional recommendations to maintain optimal levels of these nutrients to promote eBMD and prevent osteoporosis.
Authors
- Bin Yang (ORCID: https://orcid.org/0000-0001-7948-3823)
- Zhonghua Liu (ORCID: https://orcid.org/0000-0002-3849-6019)
- Sirui Zheng
- Mengyu Fan (ORCID: https://orcid.org/0000-0002-6452-3383)
- Xunying Zhao (ORCID: https://orcid.org/0000-0002-6754-9773)
- Xia Jiang (ORCID: https://orcid.org/0000-0001-5878-8986)
- Xueyao Wu (ORCID: https://orcid.org/0000-0001-6856-0520)
- Xin Song (ORCID: https://orcid.org/0000-0001-5263-5698)
- Chenjiarui Qin (ORCID: https://orcid.org/0009-0008-0183-5348)
- Tao Han (ORCID: https://orcid.org/0000-0003-4216-6968)
- Jiaqiang Liao (ORCID: https://orcid.org/0000-0002-3402-3011)
- Yong Zhong (ORCID: https://orcid.org/0000-0002-7450-1794)
- Jiaojiao Hou
- Rong Xiang (ORCID: https://orcid.org/0000-0002-6588-2724)
- Jinyu Zhou (ORCID: https://orcid.org/0009-0003-3346-4805)
- Li Zhang (ORCID: https://orcid.org/0000-0002-0324-5092)
- Changfeng Xiao
- Jinyu Xiao (ORCID: https://orcid.org/0000-0003-2318-313X)
- Jiangbo Zhu (ORCID: https://orcid.org/0000-0002-1400-2854)
- Qin Deng
- Yang Qu (ORCID: https://orcid.org/0009-0006-7485-959X)
- Jiayuan Li (ORCID: https://orcid.org/0000-0002-2920-1637)
- Mingshuang Tang
- Linna Sha (ORCID: https://orcid.org/0009-0005-7117-8804)
- Ting Yu
Institutions
- Sichuan University (CN)
- West China Medical Center of Sichuan University (CN)
- Karolinska Institutet (SE)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- European Journal of Nutrition
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1007/s00394-025-03665-2
- Citations
- 3
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 5.45
Funders
- Karolinska Institutet