Acute and subacute cardiovascular effects of synthetic cannabinoid JWH-018 in rat
JWH-018 has significant cardiovascular risks, causing heart rate dysregulation, hypotension, arrhythmias, and ischemic damage. These effects depend on dose and duration. The study highlights the potential dangers of synthetic cannabinoids, emphasizing that they should not be considered safe alternatives to natural cannabis.
Authors
- Mücahit Oruç (ORCID: https://orcid.org/0000-0002-0132-6243)
- Emine Şamdancı (ORCID: https://orcid.org/0000-0002-0034-5186)
- Pelin Koparır (ORCID: https://orcid.org/0000-0002-3981-9748)
- Osman Çelbiş (ORCID: https://orcid.org/0000-0003-2360-6905)
- Semih Petekkaya
- Hakan Parlakpınar (ORCID: https://orcid.org/0000-0001-9497-3468)
- Onural Özhan (ORCID: https://orcid.org/0000-0001-9018-7849)
- Özcan Soylu
- Necip Ermiş (ORCID: https://orcid.org/0000-0001-6781-7478)
- Ahmet Acet (ORCID: https://orcid.org/0000-0003-1131-1878)
Institutions
- Çanakkale Onsekiz Mart Üniversitesi (TR)
- Inonu University (TR)
- Malatya Devlet Hastanesi (TR)
Publication Details
- Journal
- Forensic Toxicology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1007/s11419-025-00720-9
- Citations
- 1
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu