Surgical Management of Endometrial Intraepithelial Neoplasia at Military Treatment Facilities: A Multicenter Retrospective Study
Upstaging from EIN to EC occurred in 45.3% of the 95 patients emphasizing the value of performing surgicopathologic staging in this setting. In contrast, none of the 50 EIN patients who underwent lymph node resection had positive lymph nodes indicating morbidity risk with low likelihood of clinical benefit. We identified risk factors for upstaging to EC, including age ≥65 years and endometrial thickness ≥15 mm, and confirmed the diagnostic superiority of hysteroscopy. These findings have informed clinical practice guideline recommendations for the surgical management of EIN in the Military Health System.
Authors
- Erica Hope (ORCID: https://orcid.org/0000-0002-1524-0272)
- Kathleen R. Lundeberg
- Nathan Teschan
- Stuart S. Winkler
- Rebecca Gregg
- McKayla J. Riggs (ORCID: https://orcid.org/0000-0003-4444-2110)
- J. Song (ORCID: https://orcid.org/0009-0002-0345-5652)
- Kathleen M. Darcy (ORCID: https://orcid.org/0000-0003-2888-2968)
- Chunqiao Tian (ORCID: https://orcid.org/0000-0003-3815-8025)
- Ji Won Kim
- Daniel Belgam
- Nicholas Choe
Institutions
- Henry M. Jackson Foundation (US)
- Brooke Army Medical Center (US)
- Uniformed Services University of the Health Sciences (US)
- Wilford Hall Ambulatory Surgical Center (US)
- Wright-Patterson Air Force Base (US)
- Walter Reed National Military Medical Center (US)
Publication Details
- Journal
- Military Medicine
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1093/milmed/usaf124
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Uniformed Services University of the Health Sciences