Cirrhosis and age are key determinants of HCC risk in individuals with primary sclerosing cholangitis: A multicenter longitudinal cohort study
HCC is relatively rare in patients with primary sclerosing cholangitis who do not have cirrhosis, especially in those under the age of 50. Our findings indicate that HCC monitoring for patients with PSC can be tailored based on their age and cirrhosis status.
Authors
- Stergios Kechagias (ORCID: https://orcid.org/0000-0001-7614-739X)
- Michael Ingre (ORCID: https://orcid.org/0000-0003-0678-4494)
- Annika Bergquist (ORCID: https://orcid.org/0000-0002-3858-6241)
- Emma Nilsson (ORCID: https://orcid.org/0000-0003-0586-8063)
- Christoph Schramm (ORCID: https://orcid.org/0000-0002-4264-1928)
- Kristine Wiencke (ORCID: https://orcid.org/0000-0003-1411-2276)
- Trine Folseraas (ORCID: https://orcid.org/0000-0003-2011-1923)
- Bregje Mol (ORCID: https://orcid.org/0000-0002-6428-9195)
- Elisa Catanzaro (ORCID: https://orcid.org/0009-0005-7622-6051)
- Cyriel Ponsioen
- Johan Vessby (ORCID: https://orcid.org/0000-0003-1832-6386)
- Nils Nyhlin (ORCID: https://orcid.org/0000-0002-0942-0816)
- Martti Färkkilâ (ORCID: https://orcid.org/0000-0002-0250-8559)
- Nora Cazzagon (ORCID: https://orcid.org/0000-0002-6937-8664)
- Magnus Holmer (ORCID: https://orcid.org/0000-0001-8962-6517)
- Antonio Molinaro (ORCID: https://orcid.org/0000-0003-3432-2238)
- Mårten Werner (ORCID: https://orcid.org/0000-0002-8248-1500)
Institutions
- Linköping University (SE)
- Uppsala University (SE)
- Oslo University Hospital (NO)
- Karolinska University Hospital (SE)
- University of Padua (IT)
- Universität Hamburg (DE)
- University of Oslo (NO)
- Lund University (SE)
- Örebro University (SE)
- Helsinki University Hospital (FI)
- Karolinska Institutet (SE)
- University Medical Center Hamburg-Eppendorf (DE)
- Skåne University Hospital (SE)
- University of Gothenburg (SE)
- Umeå University (SE)
Publication Details
- Journal
- Hepatology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1097/hep.0000000000001351
- Citations
- 4
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 5.29