Does unilateral reflux have a protective effect in posterior urethral valve patients?

Although some studies suggest unilateral reflux protects the contralateral kidney, others indicate worse outcomes due to dysplasia. Our findings show that renal outcomes in unilateral VUR patients are comparable with those without VUR, implying a protective effect independent of ipsilateral dysplasia. Patients with unilateral VUR exhibit similar outcomes to those without VUR. Nephrectomy should be cautiously considered due to potential protective effects.

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Publication Details

Journal
Pediatric Surgery International
Published
2025-04-16
DOI
https://doi.org/10.1007/s00383-025-06024-8
Primary Topic
Pediatric Urology and Nephrology Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Does unilateral reflux have a protective effect in posterior urethral valve patients?

Ali Cansu Bozacı, Kadir Emre Baltacı, Berk Hazır, Serdar Tekgül et al.
Pediatric Surgery International
Pediatric Urology and Nephrology Studies
article

Does unilateral reflux have a protective effect in posterior urethral valve patients?

Ali Cansu Bozacı, Kadir Emre Baltacı, Berk Hazır, Serdar Tekgül, Mesut Altan, Kamranbay Gasimov, Hasan Serkan Doğan, Gökhan Karakurt
article en

Abstract

Although some studies suggest unilateral reflux protects the contralateral kidney, others indicate worse outcomes due to dysplasia. Our findings show that renal outcomes in unilateral VUR patients are comparable with those without VUR, implying a protective effect independent of ipsilateral dysplasia. Patients with unilateral VUR exhibit similar outcomes to those without VUR. Nephrectomy should be cautiously considered due to potential protective effects.

Pediatric Surgery InternationalVol. 41(1)
Hacettepe University (TR)
Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, Hacettepe Üniversitesi
Good health and well-being
Openalex Percentile: Top 90%
Pediatric Urology and Nephrology Studies
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Does unilateral reflux have a protective effect in posterior urethral valve patients? — Ali Cansu Bozacı, Kadir Emre Baltacı, et al. · Pediatric Surgery International (2025) | TGRS Research Map | TGRS