Genome evolution of Kaposi sarcoma-associated herpesvirus (KSHV)

To understand viruses, the field needs to know their genetic makeup. To develop mechanistic models, targeted therapies, and vaccines, we need comprehensive and up-to-date sequence information on the viral strains that circulate where the diseases appear today. Our knowledge of Kaposi sarcoma herpesvirus (KSHV) sequence distribution and evolution is behind that of other human herpesviruses and RNA viruses. Here, we add to community knowledge using new technologies and artificial intelligence.

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Publication Details

Journal
Journal of Virology
Published
2025-04-16
DOI
https://doi.org/10.1128/jvi.01950-24
Citations
1
Primary Topic
Viral-associated cancers and disorders
Type
article
Field-Weighted Citation Impact
1.05

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Genome evolution of Kaposi sarcoma-associated herpesvirus (KSHV)

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Genome evolution of Kaposi sarcoma-associated herpesvirus (KSHV)

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article en
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Abstract

To understand viruses, the field needs to know their genetic makeup. To develop mechanistic models, targeted therapies, and vaccines, we need comprehensive and up-to-date sequence information on the viral strains that circulate where the diseases appear today. Our knowledge of Kaposi sarcoma herpesvirus (KSHV) sequence distribution and evolution is behind that of other human herpesviruses and RNA viruses. Here, we add to community knowledge using new technologies and artificial intelligence.

Journal of VirologyVol. 99(5)
University of North Carolina at Chapel Hill (US)
Instituto Nacional de Cancerología, National Institute of Dental and Craniofacial Research
Good health and well-being
Openalex Percentile: Top 23%
Viral-associated cancers and disorders
1.05
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