<scp>MK5</scp> Regulates Microglial Activation and Neuroinflammation in Experimental Stroke Models

Microglial MK5 plays a critical role in the ischemic neuroinflammatory response by regulating the phosphorylation of HSP27 and NF-κB, positioning it as a potential target for stroke treatment.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2025-04-01
DOI
https://doi.org/10.1111/cns.70395
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00

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article

MK5 Regulates Microglial Activation and Neuroinflammation in Experimental Stroke Models

Xu Gao, Li Du, Fei Wang, Xingzhi Wang et al.
1 links
CNS Neuroscience & Therapeutics
Neuroinflammation and Neurodegeneration Mechanisms
article

MK5 Regulates Microglial Activation and Neuroinflammation in Experimental Stroke Models

Xu Gao, Li Du, Fei Wang, Xingzhi Wang, Guiyun Cui, Ye Pang, Wenqi Mao, Yangdanyu Li
article en

Abstract

Microglial MK5 plays a critical role in the ischemic neuroinflammatory response by regulating the phosphorylation of HSP27 and NF-κB, positioning it as a potential target for stroke treatment.

CNS Neuroscience & TherapeuticsVol. 31(4)
Xuzhou Medical College (CN)
National Natural Science Foundation of China, Government of Jiangsu Province, Xuzhou Medical University
Good health and well-being
Openalex Percentile: Top 90%
Neuroinflammation and Neurodegeneration Mechanisms
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