Characterization and therapeutic potential of phage vB_Eco_ZCEC08 against multidrug-resistant uropathogenic Escherichia coli
vB_Eco_ZCEC08 phage demonstrates strong selective lytic activity against UPEC in the absence of any lysogenic behavior. These properties coupled with inherent physiochemical stability and low cytotoxicity support the development of vB_Eco_ZCEC08 as an alternative treatment for multidrug-resistant UPEC.
Authors
- Salsabil Makky
- Ian F. Connerton (ORCID: https://orcid.org/0000-0001-8652-8938)
- Assmaa H. Hussein
- Ayman El‐Shibiny (ORCID: https://orcid.org/0000-0002-7667-9457)
- Raghda Hager (ORCID: https://orcid.org/0000-0003-0414-2025)
Institutions
- Sinai University (EG)
- University of Nottingham (GB)
- Zewail City of Science and Technology (EG)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1186/s12866-025-03903-x
- Citations
- 8
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 13.73
Funders
- Science and Technology Development Fund
- Zewail City of Science and Technology