Fecal profiling reveals a common microbial signature for pancreatic cancer in Finnish and Iranian cohorts
This study highlights the potential of gut microbes as biomarkers for noninvasive PC screening and the development of targeted therapies, emphasizing the need for further research to validate these findings in diverse populations. A comprehensive understanding of the role of the gut microbiome in PC could significantly enhance early detection efforts and improve patient outcomes.
Authors
- Reza Ghanbari (ORCID: https://orcid.org/0000-0003-3876-7584)
- Mehdi Azizmohammad Looha (ORCID: https://orcid.org/0000-0002-0700-1431)
- Marja Tiirola (ORCID: https://orcid.org/0000-0001-5589-3748)
- Pauli Puolakkainen (ORCID: https://orcid.org/0000-0003-2489-4371)
- Farhad Zamani (ORCID: https://orcid.org/0000-0001-7409-3412)
- Virinder Kaur Sarhadi (ORCID: https://orcid.org/0000-0003-2503-8198)
- Arto Kokkola (ORCID: https://orcid.org/0000-0002-8286-0666)
- Heidelinde Sammallahti (ORCID: https://orcid.org/0000-0002-8028-4116)
- Hamid Asadzadeh Aghdaei (ORCID: https://orcid.org/0000-0001-5589-8856)
- Sakari Knuutila (ORCID: https://orcid.org/0000-0001-5592-3839)
- Amir Sadeghi (ORCID: https://orcid.org/0000-0002-9580-2676)
- Satu Pekkala (ORCID: https://orcid.org/0000-0003-3107-0813)
Institutions
- University of Helsinki (FI)
- Iran University of Medical Sciences (IR)
- Helsinki Institute of Physics (FI)
- Helsinki University Hospital (FI)
- Research Institute for Endocrine Sciences (IR)
- Shariati Hospital (IR)
- Numerola (Finland) (FI)
- Westfälische Hochschule (DE)
- Shahid Beheshti University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
- University of Jyväskylä (FI)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1186/s13099-025-00698-0
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Helsingin Yliopisto
- Helsingin ja Uudenmaan Sairaanhoitopiiri
- Academy of Finland
- Jyväskylän Yliopisto